The period of human life is determined by the aging of tissues and living tissues is determined by the life of the cells.

The life expectancy of all species, is genetically determined. The cells divide a predetermined number of times over the life of the person making the human species has a biological limit of 120 years for men and 125 for women.

This is called Hayflick Index after the scientist who confirmed this hypothesis.

There are many theories of human aging, aging is a multifactorial phenomenon that affects all levels of biological organization and have come to apply almost 200 theories of aging.

Some of the most studied are the theory of free radicals (reactive oxygen species, nitrogen and carbonyl) and the theory related to the shortening of the telmeros. The telmeros are extensions of the chromosomes, which are shrinking as the individual ages.

To the extent that we can achieve an antioxidant to combat reactive oxygen species and protect telmeros to avoid shortening soon, we will be preventing cellular aging.

For many years the scientific world was surprised by the longevity and quality of life of people in a Mediterranean diet, particularly the French and for this reason this phenomenon is called French Paradox.

As scientists explain prune a diet rich in fats, olive oil, wine, nuts and cheeses, will result in perfect health of the arteries and tissues?

In 1991 the scientist Leonard Guarente, yeast and flies showed that an enzyme called sirtuins was necessary to prolong the life of cells. In 2003 the scientist David Sinclair, discovered that sirtuins could be activated by natural compounds (polyphenols, flavonoids) including the most studied is the Resveratrol.

Resveratrol act as modulators of Sirtuins and these enzymes protect from oxidative stress (caused by free radicals) and also slow down telmeros shortening of chromosomes. They are constituted as a factor preventing cellular aging, tissue and therefore the aging of the individual.

Resveratrol is a flavonoid present in more than 70 plant species (grapes, wine and juice, olives, nuts, berries, oysters) that has antioxidant properties and anticancergenas, so food and drinks containing it are considered healthy or recommended for health.

Also been demonstrated to be healthier in the typical application (on the skin), so have developed cosmecuticos containing this active ingredient, which prevent chronological and biological aging of the skin (unaesthetic spots, wrinkles, dehydration), becoming advanced treatment option.